Advantage of Metabolic GI Surgery

  • Cure for Type 2 Diabetes
  • Help with sleep apnea
  • Reduces the risk of high blood cholesterol
  • Avoid weight problems in the spine, knees, ankles and hips
  • Reduces long term cardiovascular risk of heart attack, stroke
  • It offers greater benefits than any other surgery for obesity

Prevention is better than cure. Yet, in medicine, we get so few opportunities to truly prevent new diseases. And it is a big one, the prevention of diabetes

The metabolic surgery, help to ensure the remission of Type 2 Diabetes

Why is metabolic surgery the most viable option compared to other diabetes treatments?

Metabolic surgery is the most radical departure from mainstream approaches to the management of diabetes since the introduction of insulin in the 1920s. They are based on findings from a large body of work, including 11 randomized clinical trials conducted over the past decade.

International Diabetes Federation in 2016 recommends that surgery be considered early in the management of disease in obese patients, and not only as a last resort.

Link: https://www.idf.org/component/attachments/attachments.html?id=1585&task=download

Why 3E? – efficacy, efficiency, cost effective of metabolic surgery

Efficacy

– Type 2 diabetes is a progressive disease, characterized by continuing deterioration of insulin secretion over time. This leads to increasing need for medication with persistent or worsening glycemic control may increase the risk of developing diabetes complications (i.e. heart attacks and strokes, kidney failure, eye disease and blindness etc). studies show that < 50% patients have good control of diabetes despite multiple medications.

– Metabolic surgery/ Bariatric surgery, can results in dramatic improvement of type 2 diabetes, hypertension, dyslipidemia, and reduction of overall mortality. These effects are postulated due to weight loss effect and mechanism of calorie intake limitation, alteration of gut hormone, changes of gut microbiota and bile acids

– Success rate Effect is validated by randomized clinical results of STAMPEDE trial, which included 140 patients with a BMI of 27 to 43 kg/m2. The trial reported 12-month HbA1c levels of 6.0% or less in around 40% of patients who underwent surgery (gastric bypass or sleeve gastrectomy), compared with 12% of those who received medical therapy.

Efficiency

– Besides providing excellent control of diabetes and weight loss, metabolic surgery has several additional benefits, including improvement of hyperlipidemia, hypertension and sleep apnea.

– the incidence of cancer is reduced in obese patients who have had bariatric surgery. Most importantly, several reports have consistently shown that in patients with diabetes and severe obesity, surgery increases long-term survival.

– Timing of surgery- studies show patient with shorter duration of DM < 8yrs, not on insulin and preserve pancreatic function who has metabolic surgery will gain the maximal benefit for diabetes remission.

Cost Effective

– Failure of conventional weight loss therapy. Significant weight loss through lifestyle modification and medical methods is modest at best and is rarely sustained in obese, and particularly severely obese people.

– Medical options for controlling blood glucose levels are also unfortunately less effective in severely obese people.

– A number of medications used for treating type 2 diabetes, including insulin, can result in weight gain/ side effect.

– However, rates of diabetes are rising rapidly in low- and middle-income countries, where surgery is not likely to be available for most patients. But if handled the right way, the inclusion of surgery as an option could influence diabetes care as a whole.

– Several economic analyses suggest that the costs of surgery (roughly US$20,000–25,000 per procedure in the United States) may be recouped within 2 years through reduced spending on medication and care.

Recommendation for Metabolic surgery

Metabolic Surgery Enters the T2DM Treatment Algorithm

How do surgery improve diabetes?